., 2000) afforded new strategies for that elucidation of CB receptor mediated effects. Numerous scientific studies have shown an analgesic effect with synthetic and endogenous cannabinoids in inflammatory soreness products (one example is Jaggar et al
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An additional breakthrough in the elucidation of cannabinoid pharmacology came in 1988 with the discovery of a cannabinoid receptor in rat brain (CB1, Devane et al